CORDIS Project
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This project develops a novel therapeutic approach using a fusion protein that combines interleukin-2 with antibodies targeting inflammation markers. The goal is to enhance regulatory T cell activity specifically at inflammatory sites, aiming to improve treatments for autoimmune and inflammatory diseases, particularly…
As major players in the regulation of immune responses, regulatory T cells (Tregs) are important therapeutic targets for autoimmune and inflammatory diseases.
Interleukin-2 (IL-2) used at low doses (IL-2LD) stimulate and expand Tregs in vivo.
While 1st-generation native IL-2LD are currently under extensive clinical evaluation, pharmaceutical companies are developing 2nd-generation IL-2 muteins with improved half-life and activity.We aim to develop 3rd-generation IL-2 specifically targeting infla…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
MEDIZINISCHE UNIVERSITAET WIEN
Austria, Wien
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Italy, Trieste
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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