CORDIS Project
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The PHOENIX project aims to develop a novel nanomedicine that reprograms the immune environment around transplanted organs, promoting long-term tolerance without systemic immunosuppression. By utilizing advanced peptide-based therapies, it seeks to enhance the success of organ transplants, particularly in kidney and li…
PROBLEM:
Today, organ transplant medicine is limited by life-long immunosuppression and vulnerability to infections, malignancies and cardiovascular diseases, and by a 20% rate of long-term graft failure.SOLUTION:
PHOENIX reprograms the local immune micro-environment around a graft organ, inducing long-term transplant tolerance without broader systemic immunosuppression.
FOUNDATIONS:
Our expert teams have already discovered novel peptide-MHC complex-based nanomedicines for the treatment of autoi…
ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
France, Rennes Cedex 9
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Ireland, Blackrock
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
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