CORDIS Project
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The MIROCALS project investigates the potential of low-dose interleukin-2 to enhance regulatory T cells in patients with Amyotrophic Lateral Sclerosis (ALS). By focusing on immune response modification, the project aims to improve survival rates and develop new therapies for this neurodegenerative disease.
Amyotrophic Lateral Sclerosis (ALS) is a fatal degenerative disorder of the brain and spinal cord affecting some 40,000 individuals in Europe, causing 11,000 deaths each year.
Our pioneering work on riluzole showed that it is possible to modify ALS progression but all subsequent trials of potential neuroprotective agents have failed.
Thus, drug development in ALS, including trial design, patient selection, and outcome measures must be re-engineered to break the current impasse.
Nerve cell death…
NIMES GROUPE HOSPITALO-UNIVERSITAIRECARREMEAU
CENTRE HOSPITALIER UNIVERSITAIRE
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
France, PARIS
Type: Company (for-profit)
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: No
ICON CLINICAL RESEARCH (U.K.) LIMITED
United Kingdom, Hampshire
Type: Company (for-profit)
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: No
Ireland, Dublin
Type: Company (for-profit)
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: No
Germany, Langen
Type: Company (for-profit)
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: No
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