CORDIS Project
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This project focuses on the physical aspects of cell-to-cell communication, specifically through ligand and receptor interactions. It utilizes DNA origami technology to create ligand nanoclusters to study their effects on intracellular signaling pathways.
Cell-to-cell communication pathways coordinate cellular functions in multicellular organisms.
Cells that are nearest neighbours can communicate through specific interactions between ligand and receptor proteins present in their respective cell membranes.
The objective of this research program is to address the hypothesis that the physical context of the ligand/receptor interaction contributes to defining the fundamental mechanisms of action of cell-to-cell communication pathways and their cellul…
KAROLINSKA INSTITUTET
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