CORDIS Project
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The project aims to enhance onchocerciasis elimination efforts in sub-Saharan Africa by comparing the effectiveness of moxidectin and ivermectin. It will conduct community trials to assess safety and efficacy, particularly in areas co-endemic with loiasis.
Onchocerciasis is a neglected tropical disease leading to blindness and associated with epilepsy.
Most cases are in sub-Saharan Africa.
The WHO has proposed that its transmission be interrupted in a third of endemic countries by 2030.
The main strategy is annual Community-Directed Treatment with Ivermectin (CDTI).
Despite nearly 3 decades of CDTI, transmission persists in several foci.
In Phase II & III clinical trials, moxidectin has shown superior efficacy compared to ivermectin, clearing Onch…
INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
HIGHER INSTITUTE FOR SCIENTIFIC AND MEDICAL RESEARCH - ISM
Cameroon, YAOUNDE 5
Type: Research institute
Activity type: Research Organisations
SME: No
MEDICINES DEVELOPMENT FOR GLOBAL HEALTH LIMITED
United Kingdom, Ely
Type: Research institute
Activity type: Research Organisations
SME: No
FONDATION CONGOLAISE POUR LA RECHERCHE MEDICALE
Congo - Brazzaville, Brazzaville
Type: Other
Activity type: Other
SME: No
IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom, LONDON
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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