CORDIS Project
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ZeNewCardio focuses on heart regeneration by utilizing zebrafish, known for their regenerative capabilities. The project aims to identify genes that promote heart healing after ischemic injury and develop new drug therapies to enhance cardiac recovery in humans.
Ischemic heart disease is a leading cause of death worldwide.
However, heart transplantation is risky, plus the number of donors does not cover the demand of patients, and alternative treatments are inefficient.
Given that adult mammalian hearts display insufficient regeneration capability to allow complete myocardial recovery, a promising treatment after infarction could be the identification of molecules unblocking cardiac self-healing/regeneration.
In that sense, zebrafish displays life-long…
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