CORDIS Project
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This project investigates the relationship between protein expression and organismal fitness in yeast. By employing advanced synthetic biology techniques, it aims to systematically analyze how variations in protein levels affect cellular functions and contribute to disease processes.
Cellular and developmental processes rely on the precise activity of the proteins that constitute them, and alteration of protein activity often causes disease phenotypes and fitness defects.
The relation between protein activity (or expression) and organismal fitness is thus a fundamental genetic property with implications for evolutionary and disease processes.
However, a systematic understanding of how protein expression relates to fitness is lacking.Here we propose a comprehensive screen of…
FUNDACIO CENTRE DE REGULACIO GENOMICA
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