CORDIS Project
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This project investigates the tumor microenvironment to identify and characterize the tissue-derived cells that support early cancer cell growth. It aims to visualize the tumor niche in vivo and explore the role of neutrophils in cancer, as well as mechanisms to block supportive activities of the niche.
The tumour microenvironment or niche is the vital non-cancerous compartment of the tumour structure.
Thus, targeting its tissue-derived cells represents a promising avenue to better therapeutic interventions.
However, knowledge about the tissue cells taking part of the tumour niche during early cancer development and later progression is lagging behind due to the difficulty of analysing and following early tissue changes in the surrounding of cancer cells in vivo.
In our research proposal we wil…
THE FRANCIS CRICK INSTITUTE LIMITED
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