CORDIS Project
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This project investigates the role of the noradrenaline system in motivational control, particularly in the context of addiction. By using optogenetics to stimulate noradrenaline neurons in specific brain areas, it aims to uncover mechanisms that govern motivation in both drug-naive and drug-exposed mice.
Motivational control is crucial for adaptive behaviors.
Conversely, disruption of motivational control leads to maladaptive behaviors and is one of the core symptoms of addiction.
Noradrenaline (NA) system, encompassing NA neurons in locus coeruleus and nucleus tractus solitiarius is well positioned to regulate motivational control; however its exact contribution is not fully understood.
Here we aim to evaluate the role of NA system activity in the ventral tegmental area (VTA) in motivational co…
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