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The VITNK project focuses on enhancing the effectiveness of natural killer cells in fighting cancer, particularly solid tumors. It investigates how vitamin metabolites influence the development and function of these immune cells to improve cancer immunotherapy.
Natural killer (NK) cells are cytotoxic innate immune cells that defend against viral infections and cancer.
As cancer is one of the leading causes of death worldwide, more effective treatment options are urgently needed.
Harnessing NK cell cytotoxicity for cancer treatment shows promise, but there is still room for improvement, particularly against solid tumours, which are difficult to treat due to challenges such as limited tumour infiltration.
Therefore, identifying targetable factors that en…
KAROLINSKA INSTITUTET
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