CORDIS Project
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This project investigates how obesity affects the body's response to chronic viral infections, focusing on tissue wasting. It aims to uncover the mechanisms involving inflammation, glucose metabolism, and immune cell function to identify potential therapeutic strategies for improving outcomes in obese individuals suffe…
Chronic viral diseases are of significant concern to the public health due to lack of effective vaccines and paucity of potent anti-viral medication.
Notably, individuals with obesity exhibit higher morbidity and mortality due to viral diseases.
However, what specific mechanisms underlie the confounding effects of obesity on the overt outcome of viral infections remains poorly understood.
In pre-clinical studies, I found that obese mice developed profound and progressive loss of fat and muscle i…
KOBENHAVNS UNIVERSITET
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