CORDIS Project
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This project investigates how viruses exploit host cell functions during infection. By silencing individual genes in human cells, researchers aim to identify critical host proteins required for the replication of three different viruses, providing insights into viral infection mechanisms and potential therapeutic targe…
Viruses are simple, obligatory, intracellular parasites that depend on the host cell for most of the steps in the replication cycle.
Not only do they rely on the cells biosynthetic machinery, they exploit cellular processes for signaling, membrane trafficking, intra-cellular transport, nuclear import and export, molecular sorting, transcriptional regulation, etc.
To access the full spectrum of host cell functions in the infection of three different viruses in an unbiased and systematic fashion,…
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
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