CORDIS Project
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This project investigates the mutation rates of RNA viruses, exploring how genetic variability affects their evolution, fitness, and adaptability. By studying various viruses, including HIV-1 and coronaviruses, the research aims to uncover mechanisms that influence viral diversity and public health implications.
RNA viruses are the fastest evolving entities in nature.
Such rapid evolution is explained by their mutation rates, which are orders of magnitude higher than those of DNA organisms.
The error-prone replication of RNA viruses also has public-health implications related to pathogenesis, antiviral research, or viral emergence.
However, current mutation rate estimates vary by more than 100-fold across different RNA viruses and sometimes over one order of magnitude for the same virus, and the causes…
UNIVERSITAT DE VALENCIA
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Spain, Ciudad Real
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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