CORDIS Project
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The ViDaMa project focuses on understanding the unique genetic features of giant viruses, particularly Mimivirus, by developing tools for reverse genetics. It aims to explore how these viruses have evolved nuclear-like functions in their viral factories, enhancing our knowledge of viral biology and improving mRNA produ…
Giant Viruses (GVs) encode thousands of ORFan genes but their study has been nearly impossible due to the lack of genetic tools for reverse genetics.
The aims of ViDaMa and the tools I designed will shed light into this Viral protein Dark Matter.
Particularly, I will study how new genes from Mimivirus were engineered during evolution to acquire nuclear-like function for their Viral Factories (VFs). VFs physically separate viral DNA replication and transcription from translation and likely segreg…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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