CORDIS Project
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This project investigates the role of autophagy in cellular immunity, particularly in response to HIV. It aims to identify proteins that regulate autophagy and their interactions with the virus to enhance understanding of immune responses.
Cellular innate immunity employs multiple ways to fight against invading pathogens, among them autophagy.
Autophagy is an evolutionarily conserved homeostatic process in which damaged or surplus proteins are engulfed by double-membranes and subsequently degraded by the lysosome.
Although initially described as non-specific, it has become evident that autophagy can selectively recognize and degrade cargos.
While many pro-autophagy and therefore anti-viral factors have been studied in detail, our…
UNIVERSITAET ULM
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