CORDIS Project
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This project explores the spatial organization of chromatin in pluripotent stem cells to understand gene regulation during differentiation. Using advanced microscopy techniques, it aims to visualize chromatin structure and its dynamics in real time.
Recently, it has become evident that the spatial organization of chromatin within nuclei is a key factor that can regulate gene silencing and expression.
This organization is particularly important in pluripotent stem cells that differentiate into all cell types of the body through chromatin remodelling coupled to altered gene expression.
Therapeutic use of these cells demands precise control over chromatin structure to direct differentiation.
However, chromatin structure remains poorly resolved…
FUNDACIO INSTITUT DE CIENCIES FOTONIQUES
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