CORDIS Project
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This project aims to develop innovative vaccine candidates against the fungal pathogen Candida albicans, which causes severe infections in immunocompromised patients. By employing a multi-valent approach that chemically links multiple protein antigens, the project seeks to enhance vaccine efficacy and address the chall…
The fungal pathogen Candida albicans is the most pathogenic of the Candida species and causes millions of superficial mucosal infections and approximately 200,000 deaths per annum due to invasive and disseminated disease in susceptible patient populations.
Fungal infections in immunocompromised patients have an unacceptably high mortality rate of approximately 40%, and the yearly healthcare expenditure for the treatment of fungal diseases is estimated to be $15 billion.
The clinical treatment of…
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