CORDIS Project
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This study investigates how cells organize their genomes during differentiation and how this organization affects cell function. It aims to understand the dynamics of genomic interactions and nuclear architecture in various cell types, particularly during fat cell development.
This proposed study addresses a major issue in the field of genome biology: how cells adopt specific genome configuration during differentiation, how is it maintained, and how properties of nuclear architecture relate to cell
function.Although spatial clustering of genes and regulatory elements is correlated with transcription status and epigenetic states, it is not clear which mechanisms drive, which features follow, and what is the regulatory role of nuclear
organization.Our studies in numerou…
BAR ILAN UNIVERSITY
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