CORDIS Project
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This project focuses on revolutionizing cryo electron tomography (cryo-ET) by automating the sample preparation process, which is currently time-consuming and inefficient. The new workflow aims to significantly reduce preparation time and costs while increasing the yield of usable samples, thereby enhancing structural…
The interest for cryo electron microscopy (cryo-EM) has risen tremendously since the Nobel Prize in Chemistry 2017 was given for Cryo-EM.
The next step in Cryo EM, Cryo Electron Tomography (cryo-ET), makes it possible to resolve tertiary and quaternary protein structure interactions in relevant biological samples such as cells and bacteria.
However, in the current cryo-ET workflow the sample preparation is the bottleneck.
Today, sample preparation is a manual process of 4-8 hours, involves 22 st…
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