CORDIS Project
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This project aims to enhance understanding of the immune response to HIV by analyzing the interactions between the virus and CD8 T cells during acute infection. It seeks to inform the design of vaccines that elicit effective T cell responses to combat HIV.
There is an urgent need to develop effective prophylactic and therapeutic vaccines to combat the human immunodeficiency virus (HIV)/AIDS pandemic, currently responsible for ~2 million deaths/year worldwide.
The challenges encountered in developing vaccines to elicit broadly-neutralizing antibodies capable of blocking infection with diverse HIV strains, together with the wealth of evidence showing the importance of HIV-specific CD8 T cells in control of virus replication, have prompted efforts to…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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