CORDIS Project
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This project investigates the structure, function, and dynamics of subdomains within the endoplasmic reticulum, a key organelle in cells. By using advanced screening techniques in yeast and mammals, the research aims to enhance our understanding of how these subdomains are formed and maintained, which is crucial for va…
The endoplasmic reticulum (ER) is the cellular organelle that serves as the entry site into the secretory pathway.
Although the ER has a single continuous membrane, it is functionally divided into subdomains (SDs).
These specialized regions allow the ER to carry out a multitude of functions such as folding, maturation, quality control and export, of all secreted and most membrane bound proteins; lipid biosynthesis; ion homeostasis; and communication with all other organelles.
The ER is therefore…
WEIZMANN INSTITUTE OF SCIENCE
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