CORDIS Project
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uKNEEversal aims to create a human model of osteoarthritis using organs-on-chips technology. This innovative approach seeks to replicate the complexity of the disease in vitro, enabling better understanding and development of effective therapies for osteoarthritis.
uKNEEversal aims at generating a comprehensive in vitro human model of Osteoarthritis (OA) to fill lacks of existing pre-clinical tools and open perspectives to investigate OA mechanisms and therapies.
Degenerative joint diseases, among which OA is the most prevalent, represent the second cause of disability worldwide.
Available pharmacological options are limited and focus on the reduction of symptoms, being unable to factually reverse the pathology.
One of the major obstacles towards the devel…
POLITECNICO DI MILANO
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