CORDIS Project
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UbiCODE focuses on understanding protein modifications by the Ubiquitin family, which regulate various cellular functions. The project aims to decipher the complex interactions and modifications that influence protein stability and activity, with implications for treating diseases like cancer and neurodegeneration.
Essential role of protein modification by members of the Ubiquitin family:
Post-translational modifications (PTM) by members of the Ubiquitin (Ub) family represent an efficient way to regulate protein function at several levels: to change their localisation, activity, their interaction with partner proteins or their stability at the right time and cellular compartment, according to the cell requirements.
Defects in this homeostatic equilibrium result in pathologies such as cancer, neurodegenerat…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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Leiden University Medical Center
Netherlands, Leiden
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
United Kingdom, Liverpool
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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