CORDIS Project
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This project explores a novel antimicrobial pathway in mammals that protects against Salmonella Typhi, the cause of typhoid fever. By investigating the mechanisms of this pathway, it aims to identify new therapeutic targets for treating bacterial infections.
This programme will identify critical host mechanisms that kill bacterial pathogens by exploring a novel mammalian antimicrobial pathway, which I discovered.
This pathway protects non-susceptible hosts from typhoid fever.
Typhoid fever is caused by Salmonella Typhi, a unique intracellular pathogen that kills more than 200,000 humans per year.
Yet, Salmonella Typhi does not infect other mammalian species, such as mice.
An understanding of the mechanisms that protect mice from Salmonella Typhi…
THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN
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