CORDIS Project
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This project investigates the molecular mechanisms of microtubule nucleation by the γ-tubulin ring complex, which is essential for cell function. By utilizing advanced techniques in biochemistry and microscopy, it aims to enhance our understanding of microtubule organization and its implications in diseases like cancer…
Cells regulate the nucleation of microtubule polymerization locally and temporally, which is translated into accurate organization of the microtubule cytoskeleton, crucial for proper cell function.
It is well established that the major microtubule nucleator in animal cells, the γ-tubulin ring complex (γTuRC), is central for such regulation and its implication in disease is clear.
However, for more than 20 years, nobody was able to dissect the molecular mechanism of microtubule nucleation by γTuR…
FUNDACIO CENTRE DE REGULACIO GENOMICA
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