CORDIS Project
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This project focuses on designing molecular analogues of transition states related to the degradation of therapeutic compounds. It combines computational chemistry with experimental techniques to study the metabolism of nicotine- and tropine-based drugs, aiming to enhance their stability and reduce side effects in trea…
This project will contribute towards the molecular design of analogues of transition state structures associated with the degradation of therapeuticals.
It will train an essentially computational chemist in experimental techniques, allowing her to become an independent research with broad experience in isotopic studies.
The specific experimental training objective of the project is the determination of kinetic isotope effects to interpret the reaction mechanisms of degradation.
This will require…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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