CORDIS Project
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The project aims to enhance cancer immunotherapy by utilizing single-cell genomic technologies to understand the tumor microenvironment and develop a novel toolset, TROJAN-Cell, that reprograms the immune system to counteract tumor suppression signals, potentially leading to more effective treatments for various tumor…
Single-cell genomic technologies have transformed many fields of research.
We here seek to do just that in synthetic-immunology and immunotherapy.
At present, our understanding of the complex crosstalk within the tumor microenvironment (TME) is still piecemeal, as is our ability to effectively engineer the immune system to attack tumor cells in spite of the robust immune-suppression signaling of the tumor.
In line, current immunotherapies are effective only in a small subset of tumor types and p…
WEIZMANN INSTITUTE OF SCIENCE
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