CORDIS Project
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The TRIPOLES project aims to develop a detailed theoretical model of multipolar mitotic spindles, which are crucial for understanding chromosome segregation during cell division. By simulating various spindle architectures, the project seeks to uncover mechanisms that regulate these structures, with implications for ca…
Targeted Research Initiative for Pole Organization Leveraging Experiment and Simulation (TRIPOLES).
The mitotic spindle is responsible for segregating chromosomes into two identical sets prior to cell division.
Errors in the process can result in daughter cells having an incorrect number of chromosomes, a disorder referred to as aneuploidy.
Cells with multipolar spindles, an aberrant spindle architecture marked by three or more spindle pole bodies rather than the typical two, are particularly su…
FACULTY OF SCIENCE UNIVERSITY OF ZAGREB
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