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The TRiPoD project focuses on regulatory T cells, which play a crucial role in autoimmune diseases. It aims to analyze the T cell receptor repertoire and develop therapies based on engineered Tregs to improve treatment for conditions like type 1 diabetes and multiple sclerosis.
The discovery of regulatory T cells (Tregs) is a breakthrough in immunology: it revolutionises our understanding of autoimmune disease (AID) pathophysiology and treatment opportunities.
Treg numbers or function is defective in most mouse and human AIDs and their restoration induces clinical improvement, as we recently showed using low-dose IL-2 to induce Tregs in patients with AID.The TRiPoD project is based on 3 well supported assertions:- Tregs have huge therapeutic potential- Deep understandi…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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Germany, Heidelberg
Type: Research institute
Activity type: Research Organisations
SME: No
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