CORDIS Project
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This project examines the long-term cognitive effects of dietary management in adults with phenylketonuria (PKU). It assesses the relationship between blood phenylalanine levels and cognitive performance, aiming to inform dietary guidelines for adult patients.
Phenylketonuria (PKU) is an inherited metabolic disease which, if left untreated, results in severe mental retardation.
The main symptoms can be eliminated by following a restrictive and unpleasant diet, but it is unclear whether this diet should be maintained after childhood.
The research team for TREPAPHEN is treating one of the largest cohorts of PKU patients in the UK with records of blood levels of Phe since infancy.
These patients are the first generation to reach adulthood after treatment…
ASTON UNIVERSITY
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