CORDIS Project
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This project focuses on developing a treatment for hereditary spastic paraplegias, a group of neurodegenerative diseases. Using a genetic mouse model, researchers aim to identify strategies to reduce lipid accumulation in neurons, potentially leading to new therapies that delay disease progression.
Hereditary spastic paraplegias are a group of rare neurodegenerative diseases due to the degeneration of the long axons of cortical motor neurons.
Some complex forms of the disease are also characterized by cognitive impairment.
Currently, the only available treatments are symptomatic, act on the motor symptoms and do not prevent or delay the disease progression.
There is therefore a strong demand of clinicians as well as of patients and their families for the development of any treatment that c…
INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE
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