CORDIS Project
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This project focuses on understanding the unique RNA processing mechanism in kinetoplastids, which are parasites causing serious diseases. By employing advanced structural biology and genetic techniques, it aims to elucidate the process of trans-splicing, potentially leading to new therapeutic strategies against these…
Kinetoplastids are unicellular eukaryotic parasites responsible for severe human pathologies, such as sleeping sickness, Chagas disease and leishmaniasis.
Kinetoplastids have diverged early during evolution and harbor many intriguing cellular and molecular peculiarities.
Among these is their remarkably streamlined nuclear genome characterized by a high gene density and significantly divergent and specialized gene expression systems. A main example of such divergence is the polycistronic transcri…
UNIVERSITE DE LIEGE
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