CORDIS Project
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This project investigates how translational control of gene expression, particularly through mature transfer RNA availability, influences neuronal diversity during the development of the cerebral cortex. By employing advanced sequencing techniques and genetic manipulation in mouse models, it aims to uncover the mechani…
The cerebral cortex is a central structure of the mammalian brain, characterized by a remarkable diversity of neuronal types.
Understanding the origin of the extraordinary neuronal diversity is fundamental to understand how cortical architecture and functions emerge during development and remains a critical challenge in cellular and molecular neurobiology.While the efforts have been focused on transcriptional control, evidence for regulation at the translational level is emerging. I hypothesize…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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