CORDIS Project
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This project aims to explore the role of DNA methylation in determining cell identity and function. By using advanced genetic techniques in mice, it seeks to identify new regulators of DNA methylation and develop tools for targeted manipulation, which could enhance understanding of epigenetic mechanisms and their impli…
The development of complex organisms entails sequence-specific transcription factors and also epigenetic marks such as DNA methylation.
Methylation of DNA occurs on cytosines and can be transmitted over many cell generations to sustain epigenetic memory.
Yet we still know very little about how DNA methylation is attracted to specific sites in the genome and how this ultimately influences cellular destiny.
This is a fascinating challenge that deserves intensive investigations because DNA methylat…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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