CORDIS Project
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This project investigates the role of long non-coding RNAs in regulating glucose metabolism and their involvement in obesity-related insulin signaling issues. It explores the transgenerational effects of paternal obesity on metabolic regulation using mouse models.
Obesity and T2D affect large populations and cause a decline in life expectancy if untreated.
The pandemic proportion of obesity and inaptitude of anti-obesity approaches reflect our limited understanding of its complex environmental and genetic etiology.
Genome-wide association studies revealed that disease-associated risk variants are often situated in those 98% of the genome not encoding for proteins.
This noncoding genomic space yet does not reflect ‘Junk DNA’ but gives rise to >10,000 nonco…
SYDDANSK UNIVERSITET
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