CORDIS Project
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This project investigates the natural genetic transformation process in Streptococcus pneumoniae, focusing on the structure and function of the transformasome, which facilitates the uptake of DNA. By understanding this process, the project aims to uncover new strategies to combat antibiotic resistance and enhance our k…
Natural genetic transformation, first discovered in Streptococcus pneumoniae by Griffith in 1928, is observed in many Gram-negative and Gram-positive bacteria.
This process promotes genome plasticity and adaptability.
In particular, it enables many human pathogens such as Streptococcus pneumoniae, Staphylococcus aureus or Neisseria gonorrhoeae to acquire resistance to antibiotics and/or to escape vaccines.
For natural transformation to occur, bacteria must develop a highly regulated physiologica…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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France, Bordeaux
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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