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The TRANSCEND project investigates how specific factors influence the translation of genetic information to guide cell-fate decisions during embryonic development, particularly in cardiac cells. It aims to enhance understanding of translational control mechanisms and develop therapeutic strategies for cardiac function…
A central question in developmental biology is how the genetic information is differentially interpreted to program cell-fate decisions essential for embryogenesis.
The success of developmental cell-fate decisions relies on the accurate rewiring of the proteome to support rapid cellular identity changes.
Here, we will address the fundamental question:
How is the developmental transcriptome differentially translated in time and space to program cell-fate decisions? I hypothesize that the developm…
JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN
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