CORDIS Project
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This project explores the relationship between transcriptional arrest and chromatin stability, aiming to identify mechanisms that protect genetic integrity. It focuses on how transcription influences cellular responses and the potential implications for aging and disease.
Genomic integrity is essential for accurate gene expression and epigenetic inheritance.
On the other hand, a prolonged transcriptional arrest can challenge genome stability, contributing to genetic and epigenetic defects and the mechanisms of ageing and disease.Here we aim to identify the molecular mechanisms that couple transcriptional arrest to chromatin alteration and repair.
We wish to explore the idea that transcription suppresses cellular toxicity and preserves genetic and epigenetic inher…
BIOMEDICALSCIENCES RESEARCH CENTER ALEXANDER FLEMING
EREVNITIKO KENTRO VIOIATRIKON EPISTIMON ALEXANDROS FLEMINGK
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