CORDIS Project
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This project aims to utilize CRISPR/Cas9 technology to enhance our understanding of antiviral mechanisms by engineering HIV-1 to reveal human genes that counteract viral infections. By identifying key defense factors, the research seeks to improve strategies for preventing and treating viral diseases.
Viruses may seem smart since they rapidly develop new skills to spread in humans.
However, they are actually just masters of trial and error.
Their short generation time, enormous reproduction and high variability allows viruses to try countless variations. A few of these will enhance viral spread and, in the worst case, enable viral pandemics.
It is conceivable that viruses evolve to counteract those defence mechanisms that would otherwise be most effective against them.
Usually, it is hard to…
UNIVERSITAET ULM
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