CORDIS Project
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This project investigates the genome of Trachipleistophora hominis, a microsporidian parasite, to understand its evolutionary adaptations and metabolic dependencies on host organisms. By comparing its genome with other microsporidians, the research aims to reveal insights into the evolution of parasitism and the biolog…
Trachipleistophora hominis is a member of the microsporidia, a large group of obligate intracellular parasites of other eukaryotes including patients with HIV/AIDS.
Microsporidia were originally thought to be early-branching eukaryotes lacking mitochondria.
Recent data, key elements published by the proposed host laboratory, have now shown that they are highly reduced fungi with largely metabolically cryptic remnant mitochondria called mitosomes.
During their evolution to parasitism the genomes…
UNIVERSITY OF NEWCASTLE UPON TYNE
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