CORDIS Project
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PacingCure is developing a gene therapy product to transform heart cells into pacemaker cells, addressing severe cardiac pacing issues. This innovative approach aims to improve heart function through minimally invasive delivery methods.
PacingCure has developed BradyTx-01: a novel gene therapy medicinal product (GTMP) to cure life-threatening cardiac pacing dysfunctions by reprogramming cardiomyocytes into pacemaker cells.
BradyTx-01 is based on a novel method to optimally control transcription factor overexpression through adeno-associated Virus (AAV) mediated gene transfer.
The biological pacemaker that is created (1) improves cardiac function, (2) responds to metabolic demand, (3) can be delivered using minimally invasive te…
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Netherlands, Amsterdam
Type: Research institute
Activity type: Research Organisations
SME: No
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