CORDIS Project
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This project investigates the diverse states of cancer cells within tumors, focusing on squamous cell carcinoma. By employing advanced techniques like single-cell genomics and intravital microscopy, it aims to identify tumor states and their roles in cancer progression and treatment resistance.
It is now widely recognized that within a tumor, not all cancer cells are alike and different tumor states (TS) exist.
This process is known as tumor heterogeneity.
Some cancer cells actively proliferate, while others differentiate, migrate and give rise to metastasis, or enter in a dormant state and resist to chemotherapy.
The identification of distinct TS and the mechanisms that regulate their identities and functions is critical for our understanding of tumor heterogeneity.
The different TS c…
UNIVERSITE LIBRE DE BRUXELLES
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