CORDIS Project
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This project focuses on understanding how the metabolic environment affects T cell function in diseases like cancer. By analyzing T cell metabolism, the research aims to identify pathways that can be targeted to restore immune function and improve disease outcomes.
A successful adaptive immune response requires T cells to be able to adopt a specific metabolic phenotype.
However, indiseases such as cancer or those associated with chronic inflammation, the metabolic microenvironment in which a T cellfunctions is likely to subvert this metabolic phenotype, thereby disrupting function.A better understanding of how the microenvironment can affect T cell function would permit the development of metabolic'normalising' treatments that could restore function and pe…
THE UNIVERSITY OF BIRMINGHAM
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