CORDIS Project
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This project explores the mechanisms of MHC class II molecules in immune responses, identifying proteins that influence their function. It aims to enhance understanding of antigen presentation to develop potential therapies for autoimmune diseases.
MHC class II molecules are crucial for specific immune responses.
In a complicated series of cell biological events, they catch a peptide in the endosomal route for presentation at the plasma membrane to the immune system.
At present some 20 factors have been identified as involved in the process of MHC class II antigen presentation that are potential targets for manipulating these responses as MHC class II molecules are involved in most auto-immune diseases.
Defining further targets for manipul…
STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS
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