CORDIS Project
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This research explores the interaction between pulmonary neurons and innate lymphoid cells in regulating airway inflammation and tissue homeostasis. It aims to identify neuronal circuits involved in immune responses, contributing to new treatments for allergic diseases.
Group 2 innate lymphoid cells (ILC2) are strategically positioned at mucosal surfaces, regulating mucosal defense, tissue homeostasis and inflammation. ILC2 contribute to the pathogenesis of allergic airway diseases, and pulmonary neurons have been also implicated in allergic conditions, such as asthma.
Interestingly, recent studies demonstrated that ILC2 exert their function in the context of neuro-immune cell units that respond to environmental signals, steering mucosal immunity and repair.
Ne…
FUNDACAO D. ANNA DE SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD
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