CORDIS Project
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This project investigates how protein aggregates contribute to neurodegenerative diseases like Huntington's, ALS, and Alzheimer's. By analyzing cell cultures and mouse models, researchers aim to understand the toxicity mechanisms of these aggregates and the failure of cellular protein quality control, potentially leadi…
Formation of amyloid-like protein aggregates is the hallmark of a number of neurodegenerative diseases, but how the aggregation process is linked with cytotoxicity and cell death remains unclear.
The goal of this pro¬ject is to elucidate the basic mechanisms of aggregate toxicity and how it affects the biological system in its entirety.
We will analyse cell culture and mouse models of Huntington’s disease, amyotrophic lateral sclero¬sis and Alzheimer’s disease using a trans-disciplinary approach…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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