CORDIS Project
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TOP-GUT aims to advance human organ models derived from stem cells to replace animal testing. Focusing on the gastrointestinal tract, the project seeks to enhance understanding and application of these models for personalized medicine and drug development.
In the aging society, disease burden, such as degenerative diseases and cancer are rising while drug development successes are limited, due to high drug failure rates in the transition from animal experimentation to human patients.
This demands re-thinking of the currently used models.
Advances in stem cell biology and microfluidics have created new human organ models.
These models are neither fully understood, nor fully mimicking the complexity of the tissue.
With this new ability to build huma…
TECHNISCHE UNIVERSITAT BERLIN
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Germany, Berlin
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Denmark, Kobenhavn
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Netherlands, Utrecht
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
I3S - INSTITUTO DE INVESTIGACAO E INOVACAO EM SAUDE DA UNIVERSIDADE DO PORTO
Portugal, PORTO
Type: Research institute
Activity type: Research Organisations
SME: No
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