CORDIS Project
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The TNT project investigates the role of neutrophils and their extracellular traps in the progression of tauopathies like Alzheimer’s Disease. By analyzing the interactions between these immune cells and tau pathology, the project aims to uncover new therapeutic strategies and understand the influence of biological sex…
Tauopathies, including Alzheimer’s Disease (AD), characterized by the brain accumulation of abnormal Tau proteins, represent a significant unmet medical need.
Neuroinflammation is a hallmark of these diseases.
Although several neuroimmune regulations, notably involving microglia, have been largely studied recently, the role of neutrophils and the release of neutrophil extracellular traps (NETs) has been overlooked.
The TNT project will fill the gap as aimed to (1) characterize the temporal dynam…
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