CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates how compacted DNA within cells is organized and interacts with enzymes during gene expression. By using innovative biophysical techniques, it aims to uncover the role of DNA supercoiling in regulating gene activity.
In our cells, DNA is extremely highly compacted to fit within the cell’s nucleus.
While being compacted, the DNA still needs to remain accessible to various processes such as gene expression during the cell cycle.
So how is DNA spatially organized?
How does this compacted DNA interact with enzymes?
Does compacted DNA superstructure have a biological role?
Answering these daunting biological riddles through a targeted physics approach is the central motive of this proposal. I aim to investigate h…
TECHNISCHE UNIVERSITEIT DELFT
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
