CORDIS Project
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This project seeks to develop T cell-based immunotherapy for pancreatic ductal adenocarcinoma by utilizing tumor-infiltrating lymphocytes. The research aims to demonstrate the effectiveness of these lymphocytes in combating this aggressive cancer and to explore their characteristics and antigen specificity.
Pancreatic ductal adenocarcinoma (PDA) has a devastating prognosis and novel treatment approaches are urgently needed.
T cell-based immunotherapy making use of in vitro expanded tumor-infiltrating lymphocytes (TIL) has recently emerged as a potent therapy in melanoma, with the potential to cure even patients with advanced disease.We are currently working towards the development of TIL therapy for PDA on basis of our following findings:• Although PDA has been branded poorly immunogenic, we found…
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
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